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Lotronex Drug

The Lotronex drug, also known as "alosetron HCL", is used to treat diarrhea-predominant irritable bowel syndrome (D-IBS) in women. Clinical studies have yet to adequately confirm the benefits of the drug in men. Lotronex was removed from the market in November 2000, after a number of recorded cases of adverse reactions to the drug, including several deaths. The main concern with Lotronex is its potential to damage the intestine through severe constipation or ischemic colitis with symptoms that include fever, pain and blooded diarrhea. It is now available again through a restricted drug distribution program. Patients receiving the Lotronex drug are required to read and sign a Patient-Physician Agreement, and it can only be administered by physicians who have enrolled in a GlaxoSmithKline Lotronex Prescribing Program.

Fast Facts

  • The FDA initially removed the Lotronex drug from the market after 70 cases of adverse reactions that included five deaths.
  • Irritable Bowel Syndrome is estimated to affect nearly 20 million Americans, of which 1% are women with the condition in its severe form.

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  • Lotronex Side Effects and Lawsuits

    Lotronex, which has also been marketed under the brand name Alosetron, is a medication intended for use by wom...
    • Site: productliabilitylawyer.com

  • Laws and Liability for Prescription Drugs

    People take pharmaceutical drugs to achieve a health benefit.  They may be trying to reduce the side effects o...
    • Site: productliabilitylawyer.com
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